By Ph.D. Agarwal;Ms Srinivas Kamini A. Rao;Ashok
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Additional resources for Andrology Laboratory Manual
Human sperm receive a lot of guidance from the female reproductive system. Within the uterine environment, sialic acid binding protein (SABP), secreted by the endometrial walls, is found to bind to sperm and helps the influx of calcium during sperm capacitation (Banerjee and Chowdhury, 1995). Atrial natriuretic peptides (ANPs) in the follicular fluid have been shown to affect sperm swimming speed and act as a chemoattractant towards sperm in vitro (Zamir et al 1993; Anderson et al 1995). The female reproductive system aids in modulating sperm progression and regulates the number of sperm that enter the ampulla of oviduct, which is the site of fertilization.
60. 19 acrosome reaction and fertilization. Mol Hum Reprod 1997;3:175-94. Kanwar KC, Yanagimachi R, Lopata A. Effects of human seminal plasma on fertilizing capacity of human spermatozoa. Fertil Steril 1979;31:321-27. Overstreet JW, Katz DF, Yudin AI. Cervical mucus and sperm transport in reproduction. Semin Perinatol 1991;15:149-55. Langlais J, Roberts K. A molecular membrane model of sperm capacitation and the acrosome reaction of the mammalian spermatozoa. Gamete Res 1985;12:183-224. O’Flaherty C, de Lamirande E, Gagnon C.
Analysis of Fertilization. In: Gardner DK, Weissman A, Howles CM, Shoham Z, editors. Textbook of Assisted Reproductive Technologies: Laboratory and Clinical Perspectives. ; 2008:207-17. 42. Spandorfer SD, Avrech OM, Colombero LT, Palermo GD, Rosenwaks Z. Effect of parental age on fertilization and pregnancy characteristics in couples treated by intracytoplasmic sperm injection. Hum Reprod. 1998;13(2):334-38. 43. Spandorfer SD, Davis OK, Barmat LI, Chung PH, Rosenwaks Z. Relationship between maternal age and aneuploidy in in vitro fertilization pregnancy loss.