By John E. Hall (auth.), Donna H. Wang (eds.)
The renin-angiotensin process has been within the highlight for greater than a hundred years as a result of its very important function in blood strain rules, ion and fluid homeostasis, and tissue progress and reworking. contemporary advances in molecular genetic concepts have validated that the renin-angiotensin process might carry the most important to the pathogenesis of high blood pressure, congestive middle failure, continual renal failure, and stroke. In Angiotensin Protocols, Donna Wang and a panel of hands-on specialists describe in step by step aspect all of the significant molecular, biochemical, and sensible innovations now utilized in probing this strong approach. those diversity from using embryonic gene concentrating on to create mutant lines, to the useful research of parts of the renin-angiotensin method. Following the winning trend of the tools in Molecular Biology™ sequence, each one approach is crafted for experimental luck with exact directions, perceptive notes highlighting the main serious steps, and beneficial tips about pitfalls to avoid.
entire and hugely functional, Angiotensin Protocols interprets professional wisdom into with no trouble reproducible tools that allow all biomedical investigators effectively to discover the position of angiotensin in future health and sickness this present day.
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Med. J. 7160, 713–720. 35. , and Remuzzi, G. [on behalf of Gruppo Italiano di Studi Epidemiologici in Nefrologia (GISEN)]. (1998) Renal function and requirement for dialysis in chronic nephropathy patients on long-term ramipril: REIN follow-up trial. Lancet 352, 1252–1256. 36. , et al. (1999) Renoprotective properties of ACE-inhibition in non-diabetic nephropathies with non-nephrotic proteinuria. Lancet 354, 359–364. Three Angiotensin Paradigms in One Patient 37 37. The SOLVD Investigators. (1991) Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure.
1988) A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 332, 411–415. 69. Swales, J. D. (1994) Hypertension: the past, the present and the future, in Textbook of Hypertension (Swales, J. ), Blackwell Scientific, Oxford, pp. 1–7. Three Angiotensin Paradigms in One Patient 23 2 Three Angiotensin Paradigms in One Patient Etiology of Hypertension, Glomerular Hemodynamics, and Long-Term Glomerular Protection Cheryl L. Laffer and Fernando Elijovich 1. Introduction This chapter on new methods of molecular biology applied to the investigation of the renin–angiotensin system (RAS) contains a description of a clinical case in its first section.
Nephron 77, 197–204. 32. , and Iwao, H. (1998) Activation of glomerular mitogen-activated protein kinases in angiotensin II-mediated hypertension. J. Am. Soc. Nephrol. 9, 372–380. 33. , and Lishner, M. (1996) Long-term renoprotective effect of angiotensin-converting enzyme inhibition in noninsulin-dependent diabetes mellitus: a 7-year follow-up study. Arch. Intern. Med. 156, 286–289. 34. UK Prospective Diabetes Study Group. (1998) Efficacy of atenolol and captopril in reducing risk of macrovascular and microvascular complication in type 2 diabetes: UKPDS 39.