Cardiac Adaptations: Molecular Mechanisms by Bohuslav Ostadal (auth.), Bohuslav Ostadal, Naranjan S.

By Bohuslav Ostadal (auth.), Bohuslav Ostadal, Naranjan S. Dhalla (eds.)

This ebook summarizes current wisdom of alternative mechanisms fascinated with the advance of confident and adverse effects of cardiac edition. specific awareness is paid to the nonetheless underestimated adaptive cardiac responses in the course of improvement, to variation to the usually taking place strain and quantity overload in addition to to cardiac adjustments, caused by way of enduring workout and protracted hypoxia. Cardiac Adaptations could be of significant price to cardiovascular investigators, who will locate this e-book hugely necessary of their cardiovascular reports for locating ideas in different pathological stipulations; it's going to additionally entice scholars, fellows, scientists, and clinicians drawn to cardiovascular abnormalities.

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5 with pericardial edema, indicating that heart failure may have occurred. The ventricular myocardium exhibited thin walls, which suggested that the hearts were hypoplastic. While several early markers of cardiac differentiation and patterning showed normal expression, including Tbx5 and Hand2, the endoderm marker a-fetoprotein was upregulated. This result, combined with the observed hypoplasia, suggests the possibility that cardiac progenitor fate had been altered. This alteration is likely due to the roles of several 30 P.

Marques IJ, Leito JTD, Spaink HP et al (2008) Transcriptome analysis of the response to chronic constant hypoxia in zebrafish hearts. J Comp Physiol B Biochem 178:79–92 60. Petersen LH, Gamperl AK (2010) Effect of acute and chronic hypoxia on the swimming performance, metabolic capacity and cardiac function of Atlantic cod (Gadus morhua). J Exp Biol 213:808–819 61. Petersen LH, Gamperl AK (2010) In situ cardiac function in Atlantic cod (Gadus morhua):effects of acute and chronic hypoxia. J Exp Biol 213:820–830 62.

Brady AJ, Dubkin CH (1964) Coronary circulation in the turtle ventricle. Comp Biochem Physiol 13:119–128 20. Bass A, Ostadal B, Pelouch V et al (1973) Differences in weight parameters, myosin ATPase activity and the enzyme pattern of energy supplying metabolism between the compact and 1 Comparative Aspects of Cardiac Adaptation 21. 22. 23. 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. 38. 39. 40. 41. 42. 43. 44. 17 spongious cardiac musculature of carp (Cyprinus carpio) and turtle (Testudo Horsfieldi).

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